InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MDM2

Summary

InnateDB Protein

IDBP-477813.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MDM2

Protein Name

Mdm2 p53 binding protein homolog (mouse)

Synonyms

ACTFS; hdm2; HDMX;

Species

Homo sapiens

Ensembl Protein

ENSP00000427828

InnateDB Gene

IDBG-46431 (MDM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 932 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Experimentally validated
Total	932 [view]
Protein-Protein	915 [view]
Protein-DNA	10 [view]
Protein-RNA	1 [view]
DNA-DNA	6 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0016567	protein ubiquitination
GO:0043066	negative regulation of apoptotic process
GO:0071157	negative regulation of cell cycle arrest