Homo sapiens Protein: ERBB2IP
Summary
InnateDB Protein IDBP-478224.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ERBB2IP
Protein Name erbb2 interacting protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000426632
InnateDB Gene IDBG-24405 (ERBB2IP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 86 [view]
Protein-Protein 82 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005176 ErbB-2 class receptor binding
GO:0005178 integrin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0016049 cell growth
GO:0045087 innate immune response (InnateDB)
GO:0045104 intermediate filament cytoskeleton organization
GO:0045175 basal protein localization
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
Cellular Component
GO:0005604 basement membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009925 basal plasma membrane
GO:0030056 hemidesmosome
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR001478 PDZ domain
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00595
PF13180
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00228
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96RT1
PhosphoSite PhosphoSite-Q96RT1
TrEMBL
UniProt Splice Variant
Entrez Gene 55914
UniGene Hs.740465
RefSeq NP_001240628
HUGO HGNC:15842
OMIM 606944
CCDS CCDS58952
HPRD 06090
IMGT
EMBL AB033051 AC010359 AC025442 AF263744 AF276423 AK001180 AK304693 BC050692 BC115012 BC126464 BC144075
GenPept AAF77048 AAH50692 AAI15013 AAI26465 AAI44076 AAK69431 BAA86539 BAA91538 BAG65463