InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYO10

Summary

InnateDB Protein

IDBP-478386.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYO10

Protein Name

myosin X

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000421170

InnateDB Gene

IDBG-13359 (MYO10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0007165	signal transduction
GO:0008152	metabolic process

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0016459	myosin complex

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR000159 Ras-association
IPR000299 FERM domain
IPR000857 MyTH4 domain
IPR001609 Myosin head, motor domain
IPR001849 Pleckstrin homology domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR029071 Ubiquitin-related domain

PFAM

PF00612
PF00788
PF00784
PF00063
PF00169
PF00373

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00314
SM00139
SM00242
SM00233
SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt