Version 5.4
Homo sapiens Protein: SMARCE1
Summary
InnateDB Protein IDBP-47853.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMARCE1
Protein Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Synonyms BAF57;
Species Homo sapiens
Ensembl Protein ENSP00000367039
InnateDB Gene IDBG-47847 (SMARCE1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 115 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 115 [view]
Protein-Protein 112 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0016922 ligand-dependent nuclear receptor binding
GO:0031492 nucleosomal DNA binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007399 nervous system development
GO:0008152 metabolic process
GO:0043044 ATP-dependent chromatin remodeling
GO:0045087 innate immune response (InnateDB)
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0000228 nuclear chromosome
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0017053 transcriptional repressor complex
GO:0043234 protein complex
GO:0071564 npBAF complex
GO:0071565 nBAF complex
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969G3
PhosphoSite PhosphoSite-Q969G3
TrEMBL J3KT85
UniProt Splice Variant
Entrez Gene 6605
UniGene Hs.643780
RefSeq
HUGO HGNC:11109
OMIM 603111
CCDS
HPRD 04382
IMGT
EMBL AC004585 AC073508 AF035262 AK001532 AK095047 AK294218 BC007082 BC011017 BC063700 BT007176 CH471152 EU327017 EU327018 EU327019 EU327020
GenPept AAC04509 AAH07082 AAH11017 AAH63700 AAP35840 ACA81391 ACA81392 ACA81393 ACA81394 BAG50933 BAG52975 BAG57525 EAW60670

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca