Version 5.4
Homo sapiens Protein: ZNF540
Summary
InnateDB Protein IDBP-47859.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF540
Protein Name zinc finger protein 540
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000324598
InnateDB Gene IDBG-47857 (ZNF540)
Protein Structure
UniProt Annotation
Function May act as a transcriptional repressor. {ECO:0000269PubMed:16815308}.
Subcellular Localization Nucleus {ECO:0000269PubMed:16815308}. Cytoplasm {ECO:0000269PubMed:16815308}.
Disease Associations
Tissue Specificity Expressed in several fetal tissues, including gut, heart, brain, muscle, lung, testis and liver. {ECO:0000269PubMed:16815308}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000900 translation repressor activity, nucleic acid binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0017148 negative regulation of translation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NDQ6
PhosphoSite PhosphoSite-Q8NDQ6
TrEMBL K7EK80
UniProt Splice Variant
Entrez Gene 163255
UniGene Hs.728927
RefSeq NP_001165696
HUGO HGNC:25331
OMIM 613903
CCDS CCDS12506
HPRD 15827
IMGT
EMBL AB074186 AC022148 AK131388 AK290486 AL832100 AL832315 BC017940 BC126478 BC126480 BX537980
GenPept AAH17940 AAI26479 AAI26481 BAD18539 BAE45743 BAF83175 CAD38611 CAD91161 CAD97942

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca