InnateDB Protein
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IDBP-479197.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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UBA5
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Protein Name
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ubiquitin-like modifier activating enzyme 5
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000418807
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InnateDB Gene
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IDBG-57120 (UBA5)
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Protein Structure
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Function |
E1-like enzyme which activates UFM1 and SUMO2. {ECO:0000269PubMed:15071506, ECO:0000269PubMed:18442052, ECO:0000269PubMed:20368332}.
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Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:18442052}. Nucleus {ECO:0000269PubMed:18442052}. Note=Localizes mainly in cytoplasm, while it mainly localizes to the nucleus in presence of SUMO2.
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Disease Associations |
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Tissue Specificity |
Widely expressed. {ECO:0000269PubMed:16328888}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
55
[view]
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Protein-Protein |
54
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000594
UBA/THIF-type NAD/FAD binding fold
IPR009036
Molybdenum cofactor biosynthesis, MoeB
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PFAM |
PF00899
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9GZZ9
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PhosphoSite |
PhosphoSite-Q9GZZ9
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TrEMBL |
C9J5W5
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UniProt Splice Variant |
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Entrez Gene |
79876
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UniGene |
Hs.707919
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RefSeq |
XP_006713815
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HUGO |
HGNC:23230
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OMIM |
610552
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CCDS |
CCDS3077
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HPRD |
15598
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IMGT |
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EMBL |
AB154406
AC020632
AK026904
AK027563
AL136757
AY253672
BC009737
CH471052
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GenPept |
AAH09737
AAP79600
BAB15587
BAB55199
BAD15375
CAB66691
EAW79189
EAW79191
EAW79192
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