Homo sapiens Protein: ONECUT2
Summary
InnateDB Protein IDBP-479265.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ONECUT2
Protein Name one cut homeobox 2
Synonyms OC-2; OC2;
Species Homo sapiens
Ensembl Protein ENSP00000419185
InnateDB Gene IDBG-3735 (ONECUT2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0001889 liver development
GO:0001952 regulation of cell-matrix adhesion
GO:0002064 epithelial cell development
GO:0006351 transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0009887 organ morphogenesis
GO:0030335 positive regulation of cell migration
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031016 pancreas development
GO:0031018 endocrine pancreas development
GO:0042384 cilium assembly
GO:0045165 cell fate commitment
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048935 peripheral nervous system neuron development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR003350 CUT domain
IPR009057 Homeodomain-like
IPR010982 Lambda repressor-like, DNA-binding domain
PFAM PF00046
PF02376
PF13413
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95948
PhosphoSite PhosphoSite-O95948
TrEMBL
UniProt Splice Variant
Entrez Gene 9480
UniGene Hs.587951
RefSeq NP_004843
HUGO HGNC:8139
OMIM 604894
CCDS CCDS42440
HPRD 05354
IMGT
EMBL AC090340 Y18198
GenPept CAB38253