InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PGM3

Summary

InnateDB Protein

IDBP-479293.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PGM3

Protein Name

phosphoglucomutase 3

Synonyms

AGM1; IMD23; PAGM; PGM 3;

Species

Homo sapiens

Ensembl Protein

ENSP00000424874

InnateDB Gene

IDBG-93783 (PGM3)

Protein Structure

UniProt Annotation

Function

Interconverts GlcNAc-6-P and GlcNAc-1-P.

Subcellular Localization

Disease Associations

Tissue Specificity

Found in many tissues except lung. Relatively high expression in pancreas, heart, liver, and placenta, and relatively low expression in brain, skeletal muscle and kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004610	phosphoacetylglucosamine mutase activity
GO:0016868	intramolecular transferase activity, phosphotransferases

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006041	glucosamine metabolic process
GO:0006048	UDP-N-acetylglucosamine biosynthetic process
GO:0006488	dolichol-linked oligosaccharide biosynthetic process
GO:0018279	protein N-linked glycosylation via asparagine
GO:0030097	hemopoiesis
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005575	cellular_component
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR005843 Alpha-D-phosphohexomutase, C-terminal
IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
IPR016657 Phosphoacetylglucosamine mutase

PFAM

PF00408
PF02878
PF02879

PRINTS

PIRSF

PIRSF016408

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O95394