InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NRG1

Summary

InnateDB Protein

IDBP-479868.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NRG1

Protein Name

neuregulin 1

Synonyms

ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF;

Species

Homo sapiens

Ensembl Protein

ENSP00000430053

InnateDB Gene

IDBG-16182 (NRG1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding

Biological Process

GO:0009790

embryo development

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000742 Epidermal growth factor-like domain
IPR002154 Neuregulin 1-related, C-terminal
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR018250 Neuregulin

PFAM

PF00008
PF02158
PF07679
PF07686
PF00047

PRINTS

PR01089

PIRSF

SMART

SM00181
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt