InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAD51B

Summary

InnateDB Protein

IDBP-479988.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAD51B

Protein Name

RAD51 homolog B (S. cerevisiae)

Synonyms

R51H2; RAD51L1; REC2;

Species

Homo sapiens

Ensembl Protein

ENSP00000419881

InnateDB Gene

IDBG-10135 (RAD51B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	25 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003678	DNA helicase activity
GO:0003697	single-stranded DNA binding
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006259	DNA metabolic process
GO:0006260	DNA replication
GO:0006281	DNA repair
GO:0009432	SOS response

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR003593 AAA+ ATPase domain
IPR007694 DNA helicase, DnaB-like, C-terminal
IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical
IPR013632 DNA recombination and repair protein Rad51, C-terminal
IPR013765 DNA recombination and repair protein RecA
IPR014774 Circadian clock protein KaiC/DNA repair protein RadA
IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF03796
PF08423
PF00154
PF06745

PRINTS

PR00142

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt