Homo sapiens Protein: ACSL1
Summary
InnateDB Protein IDBP-480021.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACSL1
Protein Name acyl-CoA synthetase long-chain family member 1
Synonyms ACS1; FACL1; FACL2; LACS; LACS1; LACS2;
Species Homo sapiens
Ensembl Protein ENSP00000426150
InnateDB Gene IDBG-46574 (ACSL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0001676 long-chain fatty acid metabolic process
GO:0008152 metabolic process
GO:0008610 lipid biosynthetic process
GO:0019432 triglyceride biosynthetic process
GO:0033559 unsaturated fatty acid metabolic process
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
GO:0036109 alpha-linolenic acid metabolic process
GO:0043651 linoleic acid metabolic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0044539 long-chain fatty acid import
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005778 peroxisomal membrane
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000873 AMP-dependent synthetase/ligase
PFAM PF00501
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P33121
PhosphoSite PhosphoSite-P33121
TrEMBL Q108N1
UniProt Splice Variant
Entrez Gene 2180
UniGene Hs.671570
RefSeq NP_001273639
HUGO HGNC:3569
OMIM 152425
CCDS CCDS68826
HPRD 01068
IMGT
EMBL AC079257 AC084871 AK096117 AK296826 BC026290 BC050073 CH471056 D10040 DQ083029 L09229
GenPept AAB00959 AAH26290 AAH50073 AAZ30712 BAA00931 BAC04704 BAH12438 EAX04662 EAX04663 EAX04665