InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYO10

Summary

InnateDB Protein

IDBP-480257.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYO10

Protein Name

myosin X

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000426664

InnateDB Gene

IDBG-13359 (MYO10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0030507	spectrin binding
GO:0030898	actin-dependent ATPase activity
GO:0051015	actin filament binding
GO:0060002	plus-end directed microfilament motor activity

Biological Process

GO:0006200	ATP catabolic process
GO:0007411	axon guidance
GO:0008152	metabolic process
GO:0008360	regulation of cell shape
GO:0030705	cytoskeleton-dependent intracellular transport
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087	innate immune response
GO:0051489	regulation of filopodium assembly

Cellular Component

GO:0001726	ruffle
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005938	cell cortex
GO:0016459	myosin complex
GO:0030027	lamellipodium
GO:0031527	filopodium membrane
GO:0032433	filopodium tip