Version 5.4
Homo sapiens Protein: TOPBP1
Summary
InnateDB Protein IDBP-480325.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOPBP1
Protein Name topoisomerase (DNA) II binding protein 1
Synonyms TOP2BP1;
Species Homo sapiens
Ensembl Protein ENSP00000421179
InnateDB Gene IDBG-57236 (TOPBP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 77 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 77 [view]
Protein-Protein 72 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Protein Structure and Domains
PDB ID
InterPro IPR001357 BRCT domain
PFAM PF00533
PF12738
PRINTS
PIRSF
SMART SM00292
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 11073
UniGene Hs.664220
RefSeq
HUGO HGNC:17008
OMIM 607760
CCDS
HPRD 09678
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca