Version 5.4
Homo sapiens Protein: SNX21
Summary
InnateDB Protein IDBP-480347.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX21
Protein Name sorting nexin family member 21
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000418593
InnateDB Gene IDBG-78237 (SNX21)
Protein Structure
UniProt Annotation
Function May be involved in several stages of intracellular trafficking. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in fetus liver, but only weakly expressed in brain, skeleton muscle, smooth muscle, and cardiac muscle, kidney, and adrenal gland. {ECO:0000269PubMed:12459172}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR001440 Tetratricopeptide TPR1
IPR001683 Phox homologous domain
PFAM PF00515
PF00787
PRINTS
PIRSF
SMART SM00312
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969T3
PhosphoSite PhosphoSite-Q969T3
TrEMBL Q8WY78
UniProt Splice Variant
Entrez Gene 90203
UniGene Hs.612734
RefSeq NP_219489
HUGO HGNC:16154
OMIM
CCDS CCDS13377
HPRD 16641
IMGT
EMBL AF258570 AF395845 AF523834 AK091359 AK095851 AK293443 AL008726 AL591562 BC019823 CH471077
GenPept AAG23773 AAH19823 AAK73126 AAM77915 BAC03646 BAC04637 BAG56946 CAC39140 CAI20243 CAI20244 EAW75799

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca