InnateDB Protein
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IDBP-481061.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FER
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Protein Name
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fer (fps/fes related) tyrosine kinase
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Synonyms
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FerT; Pe1Fe10; Pe1Fe13; Pe1Fe3; Pe1Fe6; PPP1R74; TYK3;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000421951
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InnateDB Gene
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IDBG-36195 (FER)
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Protein Structure
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|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
21
[view]
|
Protein-Protein |
21
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
4 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004713
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protein tyrosine kinase activity
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GO:0005154
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epidermal growth factor receptor binding
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Biological Process |
GO:0008283
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cell proliferation
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GO:0018108
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peptidyl-tyrosine phosphorylation
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GO:0030335
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positive regulation of cell migration
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GO:0031532
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actin cytoskeleton reorganization
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GO:0042058
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regulation of epidermal growth factor receptor signaling pathway
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GO:0051092
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positive regulation of NF-kappaB transcription factor activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR001060
FCH domain
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PFAM |
PF00611
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PRINTS |
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PIRSF |
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SMART |
SM00055
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TIGRFAMs |
|
Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
D6RAF9
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UniProt Splice Variant |
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Entrez Gene |
2241
|
UniGene |
Hs.738538
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RefSeq |
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HUGO |
HGNC:3655
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OMIM |
176942
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CCDS |
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HPRD |
01491
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IMGT |
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EMBL |
AC008871
AC008955
AC010228
AC011421
AC034207
AC109481
AC116428
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GenPept |
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