InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FZD6

Summary

InnateDB Protein

IDBP-481489.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FZD6

Protein Name

frizzled family receptor 6

Synonyms

FZ-6; FZ6; HFZ6; NDNC10;

Species

Homo sapiens

Ensembl Protein

ENSP00000428301

InnateDB Gene

IDBG-31669 (FZD6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0042813	Wnt-activated receptor activity

Biological Process

GO:0007166	cell surface receptor signaling pathway
GO:0007275	multicellular organismal development
GO:0016055	Wnt signaling pathway

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000539 Frizzled protein
IPR017981 GPCR, family 2-like
IPR020067 Frizzled domain

PFAM

PF01534
PF01392

PRINTS

PR00489

PIRSF

SMART

SM00063

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G5EA13

UniProt Splice Variant

Entrez Gene

8323

UniGene

RefSeq

HUGO

HGNC:4044

OMIM

603409

CCDS

HPRD

04559

IMGT

EMBL

AC025370 CH471060

GenPept

EAW91869