Version 5.4
Homo sapiens Protein: FBXL7
Summary
InnateDB Protein IDBP-481580.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL7
Protein Name F-box and leucine-rich repeat protein 7
Synonyms FBL6; FBL7;
Species Homo sapiens
Ensembl Protein ENSP00000425184
InnateDB Gene IDBG-13191 (FBXL7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007067 mitotic nuclear division
GO:0008283 cell proliferation
GO:0016567 protein ubiquitination
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0019005 SCF ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR001611 Leucine-rich repeat
IPR001810 F-box domain
IPR006553 Leucine-rich repeat, cysteine-containing subtype
PFAM PF00560
PF13504
PF13855
PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00256
SM00367
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UJT9
PhosphoSite PhosphoSite-Q9UJT9
TrEMBL
UniProt Splice Variant
Entrez Gene 23194
UniGene Hs.617802
RefSeq NP_001265246
HUGO HGNC:13604
OMIM 605656
CCDS CCDS64129
HPRD 05740
IMGT
EMBL AB020647 AC010477 AC010638 AC027332 AC091872 AC091970 AF174593 AF199356 BC075061 BC136424 CH471102
GenPept AAF04514 AAF09248 AAH75061 AAI36425 BAA74863 EAX08029

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca