InnateDB Protein
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IDBP-481785.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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WDR1
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Protein Name
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WD repeat domain 1
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Synonyms
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AIP1; HEL-S-52; NORI-1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000427687
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InnateDB Gene
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IDBG-9970 (WDR1)
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Protein Structure
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Function |
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, podosome {ECO:0000269PubMed:22721921}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
37
[view]
|
Protein-Protein |
37
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
6 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001680
WD40 repeat
IPR017986
WD40-repeat-containing domain
IPR020472
G-protein beta WD-40 repeat
|
PFAM |
PF00400
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PRINTS |
PR00320
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PIRSF |
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SMART |
SM00320
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TIGRFAMs |
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Modification |
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SwissProt |
O75083
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PhosphoSite |
PhosphoSite-O75083
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TrEMBL |
V9HWG7
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UniProt Splice Variant |
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Entrez Gene |
9948
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UniGene |
Hs.128548
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RefSeq |
NP_059830
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HUGO |
HGNC:12754
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OMIM |
604734
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CCDS |
CCDS54740
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HPRD |
09199
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IMGT |
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EMBL |
AB010427
AC005674
AC093664
AF020056
AF020260
AK291614
AL050108
AL110208
BC000201
BC002489
BC030541
EU794675
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GenPept |
AAD05044
AAD05045
AAH00201
AAH02489
AAH30541
ACJ13729
BAA31855
BAF84303
CAB43276
CAB53674
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