InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLCN3

Summary

InnateDB Protein

IDBP-482053.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLCN3

Protein Name

chloride channel 3

Synonyms

ClC-3; CLC3;

Species

Homo sapiens

Ensembl Protein

ENSP00000424540

InnateDB Gene

IDBG-44331 (CLCN3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005247	voltage-gated chloride channel activity
GO:0005254	chloride channel activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0015297	antiporter activity
GO:0030165	PDZ domain binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006810	transport
GO:0006821	chloride transport
GO:0006885	regulation of pH
GO:0034220	ion transmembrane transport
GO:0044070	regulation of anion transport
GO:0048388	endosomal lumen acidification
GO:0055085	transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005769	early endosome
GO:0005770	late endosome
GO:0005794	Golgi apparatus
GO:0009986	cell surface
GO:0012506	vesicle membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030658	transport vesicle membrane
GO:0031901	early endosome membrane
GO:0031902	late endosome membrane