Homo sapiens Protein: CREM
Summary
InnateDB Protein IDBP-482109.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CREM
Protein Name cAMP responsive element modulator
Synonyms CREM-2; hCREM-2; ICER;
Species Homo sapiens
Ensembl Protein ENSP00000420437
InnateDB Gene IDBG-69430 (CREM)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 35 [view]
Protein-Protein 27 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001630 cAMP response element binding (CREB) protein
IPR004827 Basic-leucine zipper domain
PFAM PF00170
PF07716
PRINTS PR00041
PIRSF
SMART SM00338
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PAR2
UniProt Splice Variant
Entrez Gene 1390
UniGene Hs.713133
RefSeq
HUGO HGNC:2352
OMIM 123812
CCDS
HPRD 00444
IMGT
EMBL AL117336 AL157783
GenPept