Version 5.4
| Homo sapiens Protein: PTPN20A | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-482509.4 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PTPN20A | ||||||||
| Protein Name | protein tyrosine phosphatase, non-receptor type 20A | ||||||||
| Synonyms | bA142I17.1; bA42B19.1; CT126; hPTPN20; PTPN20A; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000426355 | ||||||||
| InnateDB Gene | IDBG-72304 (PTPN20A) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000269PubMed:15790311}. Cytoplasm {ECO:0000269PubMed:15790311}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:15790311}. Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Present in many cell lines (at protein level). Widely expressed. {ECO:0000269PubMed:15790311}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000242
Protein-tyrosine phosphatase, receptor/non-receptor type IPR000387 Protein-tyrosine/Dual specificity phosphatase IPR003595 Protein-tyrosine phosphatase, catalytic IPR029021 Protein-tyrosine phosphatase-like |
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| PFAM |
PF00102
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| PRINTS |
PR00700
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| PIRSF | |||||||||
| SMART |
SM00194
SM00404 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q4JDL3 | ||||||||
| PhosphoSite | PhosphoSite-Q4JDL3 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 26095 | ||||||||
| UniGene | Hs.440733 | ||||||||
| RefSeq | XP_006726580 | ||||||||
| HUGO | HGNC:23422 | ||||||||
| OMIM | 610631 | ||||||||
| CCDS | CCDS73114 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AL358791 AL450334 AL672108 AY704141 AY704142 AY704143 AY704144 AY704145 AY704146 AY704147 AY704148 AY704149 AY704150 AY704151 AY704152 AY704153 AY704154 AY704158 AY753191 BC093750 BC113473 BC143394 BC171725 BX005072 | ||||||||
| GenPept | AAH93750 AAI13474 AAI43395 AAI71725 AAW28780 AAW28781 AAW28782 AAW28783 AAW28784 AAW28785 AAW28786 AAW28787 AAW28788 AAW28789 AAW28790 AAW28791 AAW28792 AAW28793 AAW28797 AAW88572 CAI12200 CAI14088 CAI14090 CAI15685 CAI23640 CAI23642 | ||||||||