Version 5.4
| Homo sapiens Gene: PTPN20A | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-72304.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PTPN20A | ||||||||
| Gene Name | protein tyrosine phosphatase, non-receptor type 20A | ||||||||
| Synonyms | bA142I17.1; bA42B19.1; CT126; hPTPN20; PTPN20A | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000204179 | ||||||||
| Encoded Proteins |
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20A
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:46911396-47002488 | ||||||||
| Strand | Forward strand | ||||||||
| Band | q11.22 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Mus musculus
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Hs.440733 | ||||||||
| RefSeq | NM_001042357 NM_001042358 NM_001042359 NM_001042360 NM_001042361 NM_001042362 NM_001042363 NM_001042364 NM_001042365 NM_015605 XM_005270315 XM_005277652 XM_006717755 XM_006717756 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | CCDS73105 CCDS73106 CCDS73107 CCDS73108 CCDS73109 CCDS73110 CCDS73111 CCDS73114 CCDS73115 CCDS73116 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||