Version 5.4
Homo sapiens Protein: XPNPEP1
Summary
InnateDB Protein IDBP-482803.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XPNPEP1
Protein Name X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Synonyms APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1;
Species Homo sapiens
Ensembl Protein ENSP00000421566
InnateDB Gene IDBG-88996 (XPNPEP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated
Total 44 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0010815 bradykinin catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000587 Creatinase, N-terminal
IPR000994 Peptidase M24, structural domain
IPR028980 Creatinase/Aminopeptidase P, N-terminal
PFAM PF01321
PF00557
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQW7
PhosphoSite PhosphoSite-Q9NQW7
TrEMBL Q68EA4
UniProt Splice Variant
Entrez Gene 7511
UniGene
RefSeq NP_065116
HUGO HGNC:12822
OMIM 602443
CCDS CCDS7560
HPRD 03899
IMGT
EMBL AF195530 AF272981 AK223513 AK289436 AK295756 AK304367 AL354951 AL833411 BC005126 BC007579 BC013417 BX537682 CH471066 CR456922 X95762
GenPept AAF75795 AAF97866 AAH05126 AAH07579 AAH13417 BAD97233 BAF82125 BAG58586 BAG65206 CAA65068 CAD38640 CAG33203 CAH18706 CAI14248 EAW49577

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca