InnateDB Protein
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IDBP-483097.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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RNF130
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Protein Name
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ring finger protein 130
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000430999
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InnateDB Gene
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IDBG-62047 (RNF130)
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Protein Structure
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Function |
May have a role during the programmed cell death of hematopoietic cells (By similarity). Acts as an E3 ubiquitin- protein ligase. {ECO:0000250, ECO:0000269PubMed:16549277}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269PubMed:16549277}.
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Disease Associations |
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Tissue Specificity |
Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts. {ECO:0000269PubMed:16549277}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
14
[view]
|
Protein-Protein |
14
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003137
Protease-associated domain, PA
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PFAM |
PF02225
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q86XS8
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PhosphoSite |
PhosphoSite-Q86XS8
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
55819
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UniGene |
Hs.604463
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RefSeq |
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HUGO |
HGNC:18280
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OMIM |
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CCDS |
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HPRD |
11504
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IMGT |
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EMBL |
AF155650
AY083998
BC017100
BC065244
BC082267
BC108306
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GenPept |
AAF67007
AAH17100
AAH65244
AAH82267
AAI08307
AAM08686
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