Version 5.4
Homo sapiens Gene: RNF130
Summary
InnateDB Gene IDBG-62047.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF130
Gene Name ring finger protein 130
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000113269
Encoded Proteins
IDBP-62049
ring finger protein 130
IDBP-479555
ring finger protein 130
IDBP-482885
ring finger protein 130
IDBP-483097
ring finger protein 130
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:179911651-180072118
Strand Reverse strand
Band q35.3
Transcripts
ENST00000261947 ENSP00000261947
ENST00000522208 ENSP00000429509
ENST00000521389 ENSP00000430237
ENST00000520911 ENSP00000430999
ENST00000520564
ENST00000521901
ENST00000519708
ENST00000523487
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006915 apoptotic process
GO:0012501 programmed cell death
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020376
View Gene Order
ENSBTAG00000004856
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.144515 Hs.604463
RefSeq NM_001280801 NM_018434
HUGO
OMIM
CCDS CCDS4451 CCDS64340
HPRD 11504
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca