InnateDB Protein
|
IDBP-483466.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
SLC36A1
|
Protein Name
|
solute carrier family 36 (proton/amino acid symporter), member 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000428140
|
InnateDB Gene
|
IDBG-54482 (SLC36A1)
|
Protein Structure
|
|
Function |
Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000269PubMed:17897319}; Multi-pass membrane protein {ECO:0000269PubMed:17897319}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR013057
Amino acid transporter, transmembrane
|
PFAM |
PF01490
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q7Z2H8
|
PhosphoSite |
PhosphoSite-Q7Z2H8
|
TrEMBL |
H0YB60
|
UniProt Splice Variant |
|
Entrez Gene |
206358
|
UniGene |
Hs.597658
|
RefSeq |
|
HUGO |
HGNC:18761
|
OMIM |
606561
|
CCDS |
CCDS4316
|
HPRD |
07584
|
IMGT |
|
EMBL |
AC034205
AF516142
AK057340
AY162213
AY227111
AY227112
AY227113
BC136437
BC136438
BK001052
BX537963
GU296670
|
GenPept |
AAI36438
AAI36439
AAO11787
AAO37091
AAO37092
AAO37093
AAP47194
ADB56966
BAB71435
CAD97927
DAA01126
|
|
|