InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SLC36A1

Summary

InnateDB Gene

IDBG-54482.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC36A1

Gene Name

solute carrier family 36 (proton/amino acid symporter), member 1

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000123643

Encoded Proteins

IDBP-54484

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-380459

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-481072

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-483466

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-475036

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-484968

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-478170

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-477702

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-474350

solute carrier family 36 (proton/amino acid symporter), member 1

IDBP-810639

solute carrier family 36 (proton/amino acid symporter), member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:151437046-151492381

Strand

Forward strand

Band

q33.1

Transcripts

ENST00000243389	ENSP00000243389
ENST00000429484	ENSP00000395640
ENST00000520111	ENSP00000429796
ENST00000520701	ENSP00000428140
ENST00000521925	ENSP00000430305
ENST00000517945	ENSP00000427804
ENST00000521351
ENST00000519829	ENSP00000428471
ENST00000517628	ENSP00000428738
ENST00000522185	ENSP00000430181
ENST00000616007	ENSP00000480948

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0015180	L-alanine transmembrane transporter activity
GO:0015187	glycine transmembrane transporter activity
GO:0015193	L-proline transmembrane transporter activity
GO:0015293	symporter activity

Biological Process

GO:0006811	ion transport
GO:0006865	amino acid transport
GO:0015804	neutral amino acid transport
GO:0015808	L-alanine transport
GO:0015816	glycine transport
GO:0015824	proline transport
GO:0015992	proton transport
GO:0035524	proline transmembrane transport
GO:0055085	transmembrane transport
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000020261

View Gene Order

ENSBTAG00000016094

Not yet available

Pathways

NETPATH

REACTOME

REACT_19348

Proton-coupled neutral amino acid transporters pathway

REACT_13796

Amino acid transport across the plasma membrane pathway

REACT_19397

Transport of inorganic cations/anions and amino acids/oligopeptides pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_19118

SLC-mediated transmembrane transport pathway

KEGG

hsa04974

Protein digestion and absorption pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.269004 Hs.597658

RefSeq

NM_078483 XM_005268386 XM_006714759 XM_006714760

HUGO

OMIM

CCDS

CCDS4316

HPRD

07584

IMGT

EMBL

GenPept

RNA Seq Atlas