Version 5.4
Homo sapiens Protein: ENPP2
Summary
InnateDB Protein IDBP-483575.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENPP2
Protein Name ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms ATX; ATX-X; AUTOTAXIN; LysoPLD; NPP2; PD-IALPHA; PDNP2;
Species Homo sapiens
Ensembl Protein ENSP00000429447
InnateDB Gene IDBG-33807 (ENPP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0030247 polysaccharide binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001212 Somatomedin B domain
IPR020436 Somatomedin B, chordata
PFAM PF01033
PRINTS PR00022
PIRSF
SMART SM00201
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RIB9
UniProt Splice Variant
Entrez Gene 5168
UniGene Hs.741511
RefSeq
HUGO HGNC:3357
OMIM 601060
CCDS
HPRD 03037
IMGT
EMBL AC099818 AC107960
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca