Version 5.4
Homo sapiens Protein: PIK3CB
Summary
InnateDB Protein IDBP-483742.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIK3CB
Protein Name phosphoinositide-3-kinase, catalytic, beta polypeptide
Synonyms P110BETA; PI3K; PI3KBETA; PIK3C1;
Species Homo sapiens
Ensembl Protein ENSP00000419513
InnateDB Gene IDBG-58598 (PIK3CB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0046854 phosphatidylinositol phosphorylation
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
PFAM PF00168
PF00792
PRINTS PR00360
PIRSF
SMART SM00239
SM00142
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C5C3
UniProt Splice Variant
Entrez Gene 5291
UniGene Hs.740686
RefSeq
HUGO HGNC:8976
OMIM 602925
CCDS
HPRD 04234
IMGT
EMBL AC020890 AC067728 AC117389
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca