Version 5.4
Homo sapiens Protein: MANBA
Summary
InnateDB Protein IDBP-483781.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MANBA
Protein Name mannosidase, beta A, lysosomal
Synonyms MANB1;
Species Homo sapiens
Ensembl Protein ENSP00000427322
InnateDB Gene IDBG-32051 (MANBA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004567 beta-mannosidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0046355 mannan catabolic process
Cellular Component
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich
IPR006103 Glycoside hydrolase, family 2, TIM barrel
IPR008979 Galactose-binding domain-like
IPR017853 Glycoside hydrolase, superfamily
PFAM PF00703
PF02836
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PFW2
UniProt Splice Variant
Entrez Gene 4126
UniGene Hs.674762
RefSeq
HUGO HGNC:6831
OMIM 609489
CCDS
HPRD 02008
IMGT
EMBL AC018797 AF213884
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca