Version 5.4
Homo sapiens Protein: COX7A2L
Summary
InnateDB Protein IDBP-48421.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COX7A2L
Protein Name cytochrome c oxidase subunit VIIa polypeptide 2 like
Synonyms COX7AR; COX7RP; EB1; SIG81;
Species Homo sapiens
Ensembl Protein ENSP00000234301
InnateDB Gene IDBG-48417 (COX7A2L)
Protein Structure
UniProt Annotation
Function May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 3 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004129 cytochrome-c oxidase activity
GO:0009055 electron carrier activity
Biological Process
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005746 mitochondrial respiratory chain
Protein Structure and Domains
PDB ID
InterPro IPR003177 Cytochrome c oxidase, subunit VIIa
IPR017267 Cytochrome c oxidase subunit VIIa-related, mitochondrial
PFAM PF02238
PRINTS
PIRSF PIRSF037710
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14548
PhosphoSite PhosphoSite-O14548
TrEMBL Q6FGA0
UniProt Splice Variant
Entrez Gene 9167
UniGene Hs.743790
RefSeq NP_004709
HUGO HGNC:2289
OMIM 605771
CCDS CCDS1808
HPRD 05774
IMGT
EMBL AB007618 AC006038 AF127788 AK092911 AY007643 BC005251 BC007095 BT007371 CH471053 CR542208
GenPept AAF72746 AAG32129 AAH05251 AAH07095 AAP36035 AAY15087 BAA22571 BAG52628 CAG47004 EAX00320 EAX00323

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca