InnateDB Protein
|
IDBP-484269.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
HNMT
|
Protein Name
|
histamine N-methyltransferase
|
Synonyms
|
HMT; HNMT-S1; HNMT-S2;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000419415
|
InnateDB Gene
|
IDBG-71109 (HNMT)
|
Protein Structure
|
|
Function |
Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
|
Subcellular Localization |
Cytoplasm.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
9
[view]
|
Protein-Protein |
6
[view]
|
Protein-DNA |
3
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0046539
|
histamine N-methyltransferase activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
|
PFAM |
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P50135
|
PhosphoSite |
PhosphoSite-P50135
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
3176
|
UniGene |
Hs.738792
|
RefSeq |
|
HUGO |
HGNC:5028
|
OMIM |
605238
|
CCDS |
CCDS33297
|
HPRD |
05575
|
IMGT |
|
EMBL |
AC093674
AF523356
AF523357
AF523358
AF523359
AF523360
AH012839
AK313804
BC005907
BC020677
CH471058
D16224
U08092
U44106
U44107
U44108
U44109
U44110
U44111
|
GenPept |
AAA17423
AAB18137
AAH05907
AAH20677
AAN33014
AAN33015
AAN33016
AAN33017
AAN33018
AAP42155
AAY24212
BAA03752
BAG36540
EAX11612
EAX11613
EAX11614
|
|
|