InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NR3C1

Summary

InnateDB Protein

IDBP-484649.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NR3C1

Protein Name

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Synonyms

GCCR; GCR; GCRST; GR; GRL;

Species

Homo sapiens

Ensembl Protein

ENSP00000426478

InnateDB Gene

IDBG-51637 (NR3C1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 227 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	227 [view]
Protein-Protein	201 [view]
Protein-DNA	19 [view]
Protein-RNA	7 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004883	glucocorticoid receptor activity
GO:0005496	steroid binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0042921	glucocorticoid receptor signaling pathway
GO:0043402	glucocorticoid mediated signaling pathway
GO:0045087	innate immune response (InnateDB)