InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SEC24B

Summary

InnateDB Protein

IDBP-484655.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC24B

Protein Name

SEC24 family, member B (S. cerevisiae)

Synonyms

SEC24;

Species

Homo sapiens

Ensembl Protein

ENSP00000428564

InnateDB Gene

IDBG-33788 (SEC24B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0001843	neural tube closure
GO:0002093	auditory receptor cell morphogenesis
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0003151	outflow tract morphogenesis
GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0016192	vesicle-mediated transport
GO:0018279	protein N-linked glycosylation via asparagine
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0021747	cochlear nucleus development
GO:0035909	aorta morphogenesis
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0044281	small molecule metabolic process
GO:0048208	COPII vesicle coating
GO:0060088	auditory receptor cell stereocilium organization
GO:0060425	lung morphogenesis
GO:0060463	lung lobe morphogenesis
GO:0060982	coronary artery morphogenesis
GO:0061024	membrane organization
GO:0061156	pulmonary artery morphogenesis
GO:0072358	cardiovascular system development
GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
GO:1901301	regulation of cargo loading into COPII-coated vesicle

Cellular Component

GO:0000139	Golgi membrane
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0012507	ER to Golgi transport vesicle membrane
GO:0016020	membrane
GO:0030127	COPII vesicle coat
GO:0030134	ER to Golgi transport vesicle
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR002035 von Willebrand factor, type A
IPR006895 Zinc finger, Sec23/Sec24-type
IPR006896 Sec23/Sec24, trunk domain
IPR006900 Sec23/Sec24, helical domain
IPR007123 Gelsolin-like domain
IPR012990 Sec23/Sec24 beta-sandwich

PFAM

PF00092
PF04810
PF04811
PF04815
PF00626
PF08033

PRINTS

PIRSF

SMART

SM00327

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O95487