InnateDB Protein
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IDBP-484900.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ADH7
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Protein Name
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alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
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Synonyms
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ADH4;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000420269
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InnateDB Gene
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IDBG-31333 (ADH7)
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Protein Structure
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Function |
Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
Preferentially expressed in stomach.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR011032
GroES (chaperonin 10)-like
IPR013149
Alcohol dehydrogenase, C-terminal
IPR013154
Alcohol dehydrogenase GroES-like
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PFAM |
PF00107
PF08240
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P40394
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PhosphoSite |
PhosphoSite-P40394
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TrEMBL |
E9PFG0
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UniProt Splice Variant |
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Entrez Gene |
131
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UniGene |
Hs.622106
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RefSeq |
NP_001159976
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HUGO |
HGNC:256
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OMIM |
600086
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CCDS |
CCDS54781
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HPRD |
02515
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IMGT |
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EMBL |
AK301657
AK301696
AK312854
AP001960
BC131512
CH471057
L33179
L47166
S77168
U07821
U09623
U16286
U16287
U16288
U16289
U16290
U16291
U16292
U16293
X76342
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GenPept |
AAA19002
AAA59211
AAA82165
AAB34478
AAB38424
AAC51351
AAI31513
BAG35707
BAG63133
BAG63168
CAA53960
CAA53961
EAX06101
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