Version 5.4
Homo sapiens Protein: ADAM2
Summary
InnateDB Protein IDBP-485101.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM2
Protein Name ADAM metallopeptidase domain 2
Synonyms CRYN1; CRYN2; CT15; FTNB; PH-30b; PH30; PH30-beta;
Species Homo sapiens
Ensembl Protein ENSP00000429352
InnateDB Gene IDBG-18630 (ADAM2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007229 integrin-mediated signaling pathway
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
PFAM PF01421
PF00200
PF01562
PF08516
PRINTS PR00289
PIRSF
SMART SM00050
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DWY7
UniProt Splice Variant
Entrez Gene 2515
UniGene Hs.177959
RefSeq NP_001265043
HUGO HGNC:198
OMIM 601533
CCDS CCDS64883
HPRD 03322
IMGT
EMBL AC136365 AK301734 AP005902
GenPept BAG63199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca