InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TFF3

Summary

InnateDB Protein

IDBP-485205.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TFF3

Protein Name

trefoil factor 3 (intestinal)

Synonyms

ITF; P1B; TFI;

Species

Homo sapiens

Ensembl Protein

ENSP00000430690

InnateDB Gene

IDBG-4297 (TFF3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0006952	defense response
GO:0007586	digestion
GO:0043434	response to peptide hormone

Cellular Component

GO:0005576	extracellular region
GO:0030141	secretory granule
GO:0032579	apical lamina of hyaline layer
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000519 P-type trefoil
IPR017994 P-type trefoil, chordata

PFAM

PF00088

PRINTS

PR00680

PIRSF

SMART

SM00018

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q07654

PhosphoSite

PhosphoSite-

TrEMBL

X6R3S7

UniProt Splice Variant

Entrez Gene

7033

UniGene

Hs.612366

RefSeq

NP_003217

HUGO

HGNC:11757

OMIM

600633

CCDS

CCDS33565

HPRD

02797

IMGT

EMBL

AB038162 AF432265 AP001623 AP001746 BC017859 BM743413 CH471079 L08044 L15203 U25654 U25656 U25657

GenPept

AAA36766 AAA59981 AAA83628 AAH17859 AAL28111 BAA95531 BAB13731 EAX09571