InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STX3

Summary

InnateDB Protein

IDBP-48549.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STX3

Protein Name

syntaxin 3

Synonyms

STX3A;

Species

Homo sapiens

Ensembl Protein

ENSP00000338562

InnateDB Gene

IDBG-48547 (STX3)

Protein Structure

UniProt Annotation

Function

Potentially involved in docking of synaptic vesicles at presynaptic active zones.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0005515	protein binding
GO:0050544	arachidonic acid binding

Biological Process

GO:0006836	neurotransmitter transport
GO:0006886	intracellular protein transport
GO:0006887	exocytosis
GO:0016192	vesicle-mediated transport
GO:0031175	neuron projection development
GO:0060291	long-term synaptic potentiation
GO:0061025	membrane fusion

Cellular Component

GO:0005773	vacuole
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0030141	secretory granule
GO:0030425	dendrite
GO:0030426	growth cone
GO:0031201	SNARE complex
GO:0042581	specific granule
GO:0042582	azurophil granule
GO:0043005	neuron projection
GO:0070062	extracellular vesicular exosome