InnateDB Protein
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IDBP-48839.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MS4A3
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Protein Name
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membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
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Synonyms
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CD20L; HTM4;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000350872
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InnateDB Gene
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IDBG-48835 (MS4A3)
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Protein Structure
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Function |
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP). {ECO:0000269PubMed:11781350}.
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Subcellular Localization |
Endomembrane system {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Located in the perinuclear area.
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Disease Associations |
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Tissue Specificity |
Expressed specifically in hematopoietic cells and tissues.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007237
CD20-like
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PFAM |
PF04103
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96HJ5
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PhosphoSite |
PhosphoSite-Q96HJ5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
932
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UniGene |
Hs.99960
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RefSeq |
NP_001026979
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HUGO |
HGNC:7317
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OMIM |
606498
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CCDS |
CCDS31568
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HPRD |
09403
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IMGT |
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EMBL |
AP000790
AY095480
AY258289
BC008487
BG494288
L35848
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GenPept |
AAA62319
AAH08487
AAM23312
AAP14648
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