Homo sapiens Gene: MS4A3
Summary
InnateDB Gene IDBG-48835.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MS4A3
Gene Name membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
Synonyms CD20L; HTM4
Species Homo sapiens
Ensembl Gene ENSG00000149516
Encoded Proteins
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:60056587-60071128
Strand Forward strand
Band q12.1
Transcripts
ENST00000278865 ENSP00000278865
ENST00000358152 ENSP00000350872
ENST00000395032 ENSP00000378473
ENST00000528298
ENST00000525686 ENSP00000434109
ENST00000526199
ENST00000534744 ENSP00000434117
ENST00000528952
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q96HJ5
TrEMBL E9PRW8
UniProt Splice Variant
Entrez Gene 932
UniGene Hs.99960
RefSeq NM_001031666 NM_001031809 NM_006138
HUGO HGNC:7317
OMIM 606498
CCDS CCDS31567 CCDS31568 CCDS41651
HPRD
IMGT
EMBL AP000790 AY095480 AY258289 BC008487 BG494288 L35848
GenPept AAA62319 AAH08487 AAM23312 AAP14648
RNA Seq Atlas 932