Version 5.4
Homo sapiens Protein: OSBPL8
Summary
InnateDB Protein IDBP-48996.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL8
Protein Name oxysterol binding protein-like 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000261183
InnateDB Gene IDBG-48994 (OSBPL8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:11735225}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0010891 negative regulation of sequestering of triglyceride
GO:0030336 negative regulation of cell migration
GO:0045444 fat cell differentiation
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0051897 positive regulation of protein kinase B signaling
GO:0090204 protein localization to nuclear pore
Cellular Component
GO:0016020 membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR000648 Oxysterol-binding protein
IPR001849 Pleckstrin homology domain
PFAM PF01237
PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BZF1
PhosphoSite PhosphoSite-Q9BZF1
TrEMBL Q96E43
UniProt Splice Variant
Entrez Gene 114882
UniGene Hs.734733
RefSeq NP_065892
HUGO HGNC:16396
OMIM 606736
CCDS CCDS31862
HPRD 09478
IMGT
EMBL AB040884 AC117491 AC122687 AC124943 AF323730 AF392452 AK172813 AK289997 BC012935 BC093834 BC101529 BC111728 CH471054 CR749542
GenPept AAG53411 AAH12935 AAH93834 AAI01530 AAI11729 AAL40665 BAA95975 BAD18783 BAF82686 CAH18345 EAW97325 EAW97326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca