InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ECH1

Summary

InnateDB Protein

IDBP-49593.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ECH1

Protein Name

enoyl CoA hydratase 1, peroxisomal

Synonyms

HPXEL;

Species

Homo sapiens

Ensembl Protein

ENSP00000221418

InnateDB Gene

IDBG-49591 (ECH1)

Protein Structure

UniProt Annotation

Function

Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}. Peroxisome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.

Experimentally validated
Total	29 [view]
Protein-Protein	29 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0016853	isomerase activity

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005777	peroxisome
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001753 Crotonase superfamily
IPR029045 ClpP/crotonase-like domain

PFAM

PF00378

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13011

PhosphoSite

PhosphoSite-Q13011

TrEMBL

M0QXS7

UniProt Splice Variant

Entrez Gene

1891

UniGene

RefSeq

NP_001389

HUGO

HGNC:3149

OMIM

600696

CCDS

CCDS33014

HPRD

02825

IMGT

EMBL

AC008982 AC104534 AF030246 AF030247 AF030248 AF030249 AK291860 BC011792 BC017408 CH471126 U16660

GenPept

AAB86485 AAC50222 AAH11792 AAH17408 BAF84549 EAW56824