InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NFIB

Summary

InnateDB Protein

IDBP-50420.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NFIB

Protein Name

nuclear factor I/B

Synonyms

CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3;

Species

Homo sapiens

Ensembl Protein

ENSP00000370321

InnateDB Gene

IDBG-50410 (NFIB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	2 [view]
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006260	DNA replication
GO:0006355	regulation of transcription, DNA-templated

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000647 CTF transcription factor/nuclear factor 1
IPR003619 MAD homology 1, Dwarfin-type
IPR009071 High mobility group box domain
IPR019548 CTF transcription factor/nuclear factor 1, N-terminal
IPR020604 CTF transcription factor/nuclear factor 1, DNA-binding domain

PFAM

PF00859
PF03165
PF00505
PF09011
PF10524

PRINTS

PIRSF

SMART

SM00523
SM00398

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite