Version 5.4
Homo sapiens Protein: CNDP1
Summary
InnateDB Protein IDBP-5064.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNDP1
Protein Name carnosine dipeptidase 1 (metallopeptidase M20 family)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000351682
InnateDB Gene IDBG-5062 (CNDP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis. {ECO:0000269PubMed:12473676, ECO:0000269PubMed:6616870}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity
GO:0016805 dipeptidase activity
GO:0034701 tripeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR002933 Peptidase M20
IPR011650 Peptidase M20, dimerisation domain
IPR017153 Glutathione degradosome, DUG1
PFAM PF01546
PF07687
PRINTS
PIRSF PIRSF037242
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96KN2
PhosphoSite PhosphoSite-Q96KN2
TrEMBL B4E180
UniProt Splice Variant
Entrez Gene 84735
UniGene Hs.640886
RefSeq NP_116038
HUGO HGNC:20675
OMIM 609064
CCDS CCDS12007
HPRD 09894
IMGT
EMBL AJ417564 AK303708 AY358756 BC004271 BC110295 BC113512 BC117122
GenPept AAI10296 AAI13513 AAI17123 AAQ89116 BAG64692 CAD10388

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca