InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STX5

Summary

InnateDB Protein

IDBP-51956.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STX5

Protein Name

syntaxin 5

Synonyms

SED5; STX5A;

Species

Homo sapiens

Ensembl Protein

ENSP00000294179

InnateDB Gene

IDBG-51952 (STX5)

Protein Structure

UniProt Annotation

Function

Mediates endoplasmic reticulum to Golgi transport. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Note=Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	37 [view]
Protein-Protein	37 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0005515	protein binding
GO:0047485	protein N-terminus binding

Biological Process

GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006903	vesicle targeting
GO:0016192	vesicle-mediated transport
GO:0042147	retrograde transport, endosome to Golgi
GO:0048280	vesicle fusion with Golgi apparatus

Cellular Component

GO:0000139	Golgi membrane
GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031201	SNARE complex
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane