Version 5.4
Mus musculus Protein: Tbc1d4
Summary
InnateDB Protein IDBP-531637.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d4
Protein Name TBC1 domain family, member 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000125509
InnateDB Gene IDBG-184270 (Tbc1d4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0016192 vesicle-mediated transport
GO:0031339 negative regulation of vesicle fusion
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:0032869 cellular response to insulin stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0031988 membrane-bounded vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2429660
InterPro IPR000195 Rab-GTPase-TBC domain
IPR006020 PTB/PI domain
IPR021785 Protein of unknown function DUF3350
PFAM PF00566
PF00640
PF14719
PF11830
PRINTS
PIRSF
SMART SM00164
SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q6Q8
UniProt Splice Variant
Entrez Gene 210789
UniGene Mm.409771
RefSeq NP_001074747
MGI ID
MGI Symbol Tbc1d4
OMIM
CCDS CCDS49556
HPRD
IMGT
EMBL CT025630 CT573019 CT573033
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca