Version 5.4
Mus musculus Gene: Tbc1d4
Summary
InnateDB Gene IDBG-184270.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbc1d4
Gene Name TBC1 domain family, member 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033083
Encoded Proteins
IDBP-184274
TBC1 domain family, member 4
IDBP-531637
TBC1 domain family, member 4
IDBP-540727
TBC1 domain family, member 4
IDBP-533044
TBC1 domain family, member 4
IDBP-534655
TBC1 domain family, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136111:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:101442360-101609191
Strand Reverse strand
Band E2.3
Transcripts
ENSMUST00000100340 ENSMUSP00000097913
ENSMUST00000161991 ENSMUSP00000125509
ENSMUST00000159951 ENSMUSP00000124511
ENSMUST00000161304
ENSMUST00000162617 ENSMUSP00000124909
ENSMUST00000160297
ENSMUST00000159484
ENSMUST00000159668
ENSMUST00000159664 ENSMUSP00000124734
ENSMUST00000160473
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0016192 vesicle-mediated transport
GO:0031339 negative regulation of vesicle fusion
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
GO:0032869 cellular response to insulin stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0030659 cytoplasmic vesicle membrane
GO:0031988 membrane-bounded vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136111
View Gene Order
ENSBTAG00000005760
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_199054
Translocation of GLUT4 to the plasma membrane pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
pi3kciaktpathway
Class I PI3K signaling events mediated by Akt
insulin_glucose_pathway
Insulin-mediated glucose transport
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.320639 Mm.409771
RefSeq NM_001081278 XM_006518759 XM_006518760 XM_006518763 XM_006518765
OMIM
CCDS CCDS49556
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca