Version 5.4
Mus musculus Protein: Unc5c
Summary
InnateDB Protein IDBP-531667.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Unc5c
Protein Name unc-5 homolog C (C. elegans)
Synonyms B130051O18Rik; rcm; Unc5h3;
Species Mus musculus
Ensembl Protein ENSMUSP00000117487
InnateDB Gene IDBG-196891 (Unc5c)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005042 netrin receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007420 brain development
GO:0030334 regulation of cell migration
GO:0033564 anterior/posterior axon guidance
GO:0038007 netrin-activated signaling pathway
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1095412
InterPro IPR000488 Death domain
IPR000884 Thrombospondin, type 1 repeat
IPR000906 ZU5
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR011029 Death-like domain
IPR013098 Immunoglobulin I-set
PFAM PF00531
PF00090
PF00791
PF07679
PRINTS
PIRSF
SMART SM00005
SM00209
SM00218
SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UTY3
UniProt Splice Variant
Entrez Gene 22253
UniGene Mm.24430
RefSeq
MGI ID
MGI Symbol Unc5c
OMIM
CCDS
HPRD
IMGT
EMBL AC102315 AC157492 AC158552 AC170085 AK138987
GenPept BAE23847

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca