InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dmpk

Summary

InnateDB Protein

IDBP-531784.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dmpk

Protein Name

dystrophia myotonica-protein kinase

Synonyms

DM; Dm15; DMK; MDPK; MT-PK;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118459

InnateDB Gene

IDBG-149384 (Dmpk)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0002028	regulation of sodium ion transport
GO:0006468	protein phosphorylation
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction

Cellular Component

Protein Structure and Domains

PDB ID

MGI:94906

InterPro

IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR014930 Myotonic dystrophy protein kinase, coiled coil
IPR017892 Protein kinase, C-terminal
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF08826
PF00433

PRINTS

PR00109

PIRSF

SMART

SM00133
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D6RI32

UniProt Splice Variant

Entrez Gene

13400

UniGene

Mm.6529

RefSeq

MGI ID

MGI Symbol

Dmpk

OMIM

CCDS

HPRD

IMGT

EMBL

AC145199 AC170864

GenPept