InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myl2

Summary

InnateDB Protein

IDBP-531936.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myl2

Protein Name

myosin, light polypeptide 2, regulatory, cardiac, slow

Synonyms

MLC-2; MLC-2v; Mlc2v; Mylpc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119627

InnateDB Gene

IDBG-197887 (Myl2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003785	actin monomer binding
GO:0005509	calcium ion binding

Biological Process

GO:0003007	heart morphogenesis
GO:0007507	heart development
GO:0009791	post-embryonic development
GO:0030308	negative regulation of cell growth
GO:0042694	muscle cell fate specification
GO:0048747	muscle fiber development
GO:0055003	cardiac myofibril assembly
GO:0055010	ventricular cardiac muscle tissue morphogenesis
GO:0060047	heart contraction
GO:0060048	cardiac muscle contraction

Cellular Component

GO:0015629	actin cytoskeleton
GO:0030016	myofibril

Protein Structure and Domains

PDB ID

MGI:97272

InterPro

IPR002048 EF-hand domain

PFAM

PF00036
PF13202
PF13405

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z1V1

UniProt Splice Variant

Entrez Gene

17906

UniGene

RefSeq

MGI ID

MGI Symbol

Myl2

OMIM

CCDS

HPRD

IMGT

EMBL

AC140353

GenPept